Energy Metabolism in Sepsis
نویسندگان
چکیده
منابع مشابه
Impaired energy metabolism during neonatal sepsis: the effects of glutamine.
Neonatal sepsis is an important cause of morbidity and mortality as a result of multiple organ system failure, particularly in neonates requiring total parenteral nutrition. Suitable therapies and support are needed both to prevent sepsis and to prevent multiple organ failure. After bacterial infection, pro-inflammatory cytokines trigger the antimicrobial activity of macrophages and neutrophils...
متن کاملEthyl pyruvate protects against sepsis by regulating energy metabolism.
BACKGROUND Ethyl pyruvate (EP) is a derivative of pyruvic acid that has been demonstrated to be a potential scavenger of reactive oxygen species as well as an anti-inflammatory agent. In this study, we investigated the protective effects of EP and its role in regulating the energy metabolism in the livers of cecal-ligation-and-puncture-induced septic mice. METHODS The animals were treated int...
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Introduction One of the most pronounced metabolic changes after injury, sepsis and other critical illness is increased urinary excretion of nitrogen, resulting in negative nitrogen balance. There is evidence that skeletal muscle is the major source of nitrogen in these conditions. Muscle catabolism during sepsis is mainly caused by increased protein degradation, in particular myofibrillar prote...
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133 Protective effects of exercise against sepsis-induced energy metabolism dysfunction in skeletal muscle of rats Efeitos protetores do exercício contra a disfunção do metabolismo energético induzida por sepse na musculatura esquelético de ratos Efectos del ejercicio contra la disfunción del metabolismo energético inducida por sepsis en la musculatura esquelética de ratones Carla Werlang-Coelh...
متن کاملCellular metabolism of myeloid cells in sepsis.
In recent years, it has become appreciated that immune cells have different metabolic profiles depending on their activation status. During sepsis, circulating leukocytes go through a hyperinflammatory state, which can be accompanied or followed by defective antimicrobial defenses (also described as immune tolerance or paralysis). In this review, the modulation of different cellular metabolic p...
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ژورنال
عنوان ژورنال: Annals of Surgery
سال: 1974
ISSN: 0003-4932
DOI: 10.1097/00000658-197405000-00023